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Southern Baked Spaghetti Casserole

This Southern Baked Spaghetti Casserole is a crowd-pleasing, high-protein pasta bake made with al dente pasta, lean ground beef, hearty marinara sauce, fresh Italian herbs, and a generous layer of melted cheese. Perfect for large family gatherings, potlucks, and make-ahead freezer meals. 

overhead photo of a pan of southern baked spaghetti with a served plate of spaghetti casserole next to it with a peppermill behind it

This new and improved southern baked spaghetti recipe captures the charm of down-home southern casseroles AND the warmth of traditional Italian spaghetti with meat sauce in one protein-packed, downright delicious dish!

It’s the type of heartwarming, comfort food that brings people together because what’s not to love about a hot and bubbly casserole filled with layers of al dente spaghetti, Italian-seasoned ground beef, tangy tomato sauce, and melty mozzarella cheese?

That said, if you’re looking for a crowd-size casserole that will satisfy your loved ones and leave them asking for seconds, you’ve found it! So grab your apron because this Southern baked spaghetti is a culinary masterpiece that will transport you straight to the heart of the South!

Why you’ll love this recipe

  • Quick and easy. It’s easy to make with simple ingredients yet has a ton of mouthwatering tastes and textures. 
  • Macro-friendly pasta. Made with lean ground beef and protein plus pasta, this recipe is packed with protein, but you can always adapt the recipe to align with your individual macronutrient goals. 
  • Family dinner favorite. It yields ten servings, perfect for big families and potluck-style gatherings. 
  • Freezer-friendly. Baked spaghetti freezes like a dream, so this is an excellent recipe for your make-ahead freezer meal repertoire.  

Ingredients you’ll need

ingredients for baked spaghetti casserole measured out on a counter ready to make
  • Olive oil To coat the skillet and prevent the ground beef and vegetables from sticking. 
  • Ground beef – I recommend using lean ground beef (93%) for a lighter, healthier option. 
  • Onion, green pepper, and garlic – This aromatic veggie trio adds deep savory flavor and textural complexity to the meat sauce. 
  • Diced tomatoes – For the best tomato sauce, use a can of diced tomatoes with rich flavor and a good texture, such as San Marzano
  • Marinara sauce – You can use homemade or your favorite store-bought sauce. Rao’s Homemade and Michael’s of Brooklyn are excellent options.  
  • Fresh basil and oregano – Fresh herbs are best, but you can use dried herbs if that’s what you have. Remember, you’ll only need 1 teaspoon of dried herbs per tablespoon of fresh herbs. 
  • Salt and pepper – To taste. 
  • Spaghetti – I use Barilla Protein Plus, which provides 16 additional grams of protein and has 34 fewer carbs than regular pasta for the entire recipe. A whole-grain variety would be great, too.
  • Parmesan cheese – It’s best to use parmesan shredded directly off the block for the best taste and texture. 
  • Mozzarella For the top layer of cheesy, gooey goodness!

How to make Southern Baked Spaghetti

Step 1: Brown the ground beef. Heat olive oil in a large skillet over medium heat, then add the ground beef and cook, breaking up the meat with a sturdy spoon until no longer pink. 

Step 2: Sauté the aromatics. Add the garlic, onions, and peppers, and continue cooking, stirring often, until softened. 

ground beef, peppers and onions cooked in a skillet

Step 3: Simmer the sauce. Drain the liquid from the meat mixture, then stir in the drained canned tomatoes, marinara, fresh herbs, salt, and pepper. Reduce the heat and let it simmer.

spaghetti sauce for southern spaghetti casserole simmering in a skillet

Step 4: Cook the pasta. Meanwhile, boil a large pot of salted water and cook the spaghetti al dente according to the package instructions. Drain well, and set aside. 

Step 5: Assemble the casserole. Generously grease a 9×13” baking dish, then add the spaghetti and toss it with parmesan cheese. Next, add the meat sauce and stir to combine. Finally, sprinkle shredded mozzarella over the top.  

Step 6: Bake the casserole. Transfer the dish to the 350°F preheated oven and bake, uncovered, until the cheese is melted and lightly golden (about 30 minutes). Let the casserole rest for a few minutes and enjoy!

four step photos of assembling the baked spaghetti in a casserole dish

Recipe tips

  • Modify the meat-to-sauce ratio to preference. If you like your spaghetti heavy on meat and light on sauce, stick with 24 ounces (3 cups) of marinara. If you prefer it on the saucier side, use 32 ounces (4 cups) of marinara instead.
  • Cook the spaghetti al dente. This will prevent the pasta from overcooking when baked in the casserole and becoming mushy.
  • Do not rinse the pasta. Drain the spaghetti well once it’s finished cooking, but do not rinse it. The excess starch gives the spaghetti sauce a surface to cling to. 
  • Cover the casserole with foil if needed. If the cheese appears to be browning too quickly, tent the baking dish with foil for the remainder of the baking time to prevent the cheese from burning. 

Variations

The beauty of Southern baked spaghetti is the endless customization possibilities. Here are some ideas for inspiration:

  • Ground beef substitutes – If you want to substitute ground beef, you can use ground turkey, ground chicken, ground pork, or crumbled Italian sausage.
  • Add meatballs – Before adding the top layer of cheese, add bite-size meatballs for an additional protein boost. Or, if that’s too much protein, omit the ground beef altogether and use meatballs instead. 
  • Vegetarian version – Swap the ground beef with your favorite plant-based ground “meat,” lentils, or load up on sautéed veggies like bell peppers, onion, zucchini, eggplant, mushrooms, spinach, and so on. 
  • Low carb/keto-friendly variation – Swap the pasta with cooked and cooled spaghetti squash. See this spaghetti squash and meatball casserole recipe for an example. 

Serving suggestions

Serving this with a refreshing pitcher of sweet tea and a side of Texas toast or cornbread is a no-brainer. Check out the list below for more sides dishes that go great with Southern baked spaghetti:  

photo of a spatula holding up a serving of spaghetti casserole in the dish

Storing & freezing

To store leftovers: Let the casserole cool completely, then place it in an airtight container and store it in the refrigerator for 3-4 days. Remember, if the dish sat at room temperature for more than 2 hours, it’s no longer safe to eat and should be thrown away.

To make ahead and freeze: To prep this baked spaghetti casserole ahead to freeze it for later, prepare the meat sauce and cook the spaghetti as instructed. Then, assemble the dish in a freezer-safe casserole pan with a layer of shredded mozzarella on top. Once cooled, wrap the pan with aluminum foil, and freeze it for 2-3 months. Transfer the pan to the refrigerator, and let it thaw overnight before baking. 

FAQs

Why is my baked spaghetti mushy?

If your baked spaghetti is mushy, it’s most likely overcooked. To prevent this, it’s important to boil the pasta no further than al dente and be mindful of the baking time. 

How long do you bake Southern spaghetti?

The baking time may vary depending on the size of your casserole, but as a general guideline, Southern spaghetti casserole is baked at 350°F for about 30 minutes.

How do you know when baked spaghetti is done?

Remember, the pasta and meat sauce are already cooked, so the baking step is to melt the cheese and heat everything through. With that in mind, you’ll know when it’s ready to come out of the oven because the cheese will be melted, lightly golden, and starting to bubble.

More crowd-pleasing casseroles

If you love this Southern-style spaghetti bake, I would be so grateful if you could leave a 5-star 🌟 rating in the recipe card below. I love reading your comments and feedback!

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a pan of southern baked spaghetti with a bottle of wine, peppermill, and salt jar behind it
a spatula holding a serving of baked spaghetti over a pan of casserole

Southern Baked Spaghetti Casserole

An easy and high-protein spaghetti bake made with lean ground beef, peppers and onions, diced tomatoes, marinara sauce, fresh herbs, spices, and cheese.
4.67 from 3 votes
Print Pin Rate
Course: Main
Cuisine: Italian
Prep Time: 15 minutes
Cook Time: 30 minutes
Total Time: 45 minutes
Servings: 10
Calories: 411kcal
Author: Amee

Equipment

  • 1 Large skillet
  • 1 large pot
  • 9×13 baking dish

Ingredients

  • 1 tbsp olive oil
  • 2 lbs lean ground beef I used 93% lean
  • 3 cloves garlic minced
  • 1 cup sweet onion finely chopped
  • 1 large green pepper seeded and finely chopped
  • 15 oz can of diced tomatoes drained
  • 24 oz marinara sauce you can use 32 oz if you like it really saucy
  • 1 tbsp chopped fresh basil
  • 1 tbsp chopped fresh oregano
  • 1 tsp salt you can use a little more, to taste
  • 1/2 tsp pepper
  • 14.5 oz spaghetti noodles I use the protein-plus pasta for a protein boost
  • 1/2 cup parmesan cheese shredded
  • 2 cups mozzarella shredded

Instructions

  • Preheat the oven to 350 degrees F.
  • Heat olive oil in a large skillet over medium heat. Add the ground beef and cook for 4 minutes, breaking up the meat with a sturdy spoon.
  • Add the garlic, onions, and chopped peppers. Cook until softened, about 4 minutes more.
  • Drain the liquid from the meat mixture, then stir in the drained canned tomatoes, marinara, fresh herbs, salt, and pepper. Turn the heat down to low and simmer while you cook the noodles.
  • Bring a large pot of salted water to a boil and cook the spaghetti according to the package directions. I cook it al dente, for the best texture. Drain well, and set aside.
  • Spray a 9×13 baking dish generously with olive oil spray. Add the spaghetti and toss with the parmesan cheese.
  • Spread the sauce mixture on top and stir gently to mix.
  • Top with the shredded mozzarella and bake for 30 minutes, uncovered, until lightly golden.

Notes

Tips:
    • Modify the meat-to-sauce ratio to preference. If you like your spaghetti heavy on meat and light on sauce, stick with 24 ounces (3 cups) of marinara. If you prefer it on the saucier side, use 32 ounces (4 cups) of marinara instead.
    • Cook the spaghetti al dente. This will prevent the pasta from overcooking when baked in the casserole and becoming mushy.
    • Do not rinse the pasta. Drain the spaghetti well once it’s finished cooking, but do not rinse it. The excess starch gives the spaghetti sauce a surface to cling to.
    • You can use homemade marinara for this recipe, or go with a high-quality store-bought marinara, like Rao’s Homemade or Michael’s of Brooklyn for best flavor. If you already have a favorite, go with what you love. 
*Nutrition info calculated with regular spaghetti. The Barilla Protein Plus spaghetti provides 16 G more protein and 34 G less carbs for the entire recipe, which comes out to 1.6 G more protein and 3.4 G less carbs per serving. 

Nutrition

Calories: 411kcal | Carbohydrates: 39g | Protein: 33g | Fat: 13g | Saturated Fat: 6g | Polyunsaturated Fat: 1g | Monounsaturated Fat: 5g | Trans Fat: 0.3g | Cholesterol: 77mg | Sodium: 901mg | Potassium: 769mg | Fiber: 3g | Sugar: 6g | Vitamin A: 615IU | Vitamin C: 23mg | Calcium: 227mg | Iron: 4mg
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Amee Livingston
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5 Comments

  1. I’ve been making a similar baked spaghetti dish for years. This is the first time I’ve found it on a food site. I use canned tomatoes, canned sliced mushrooms and angel hair pasta. It is by far the best spaghetti dish I’ve ever had.

    1. Tanya, it’s one of our favorites! I love angel hair, so I’ll have to try that next time!

  2. 5 stars
    I loved this. Took it to a friend’s family, but made extra for my own family. I used most of a 42 oz. jar of marinara, and tri-colored bell peppers. It was really delicious. I don’t usually like regular spaghetti, but this baked version will be a go-to from here on! Thanks!

4.67 from 3 votes (2 ratings without comment)

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